The RAISE Act imposes safety, transparency, and governance obligations on 'large developers' of frontier AI models — defined as entities that have spent over $5 million in compute on at least one frontier model and over $100 million in aggregate compute on frontier models. Core obligations include implementing and publicly publishing a written safety and security protocol before deployment, conducting annual third-party compliance audits, reporting safety incidents to the Division of Homeland Security and Emergency Services within 72 hours, and prohibiting deployment of frontier models that pose an unreasonable risk of critical harm (defined as 100+ deaths/serious injuries or $1B+ in damages via CBRN weapons or autonomous criminal AI conduct). The bill includes whistleblower anti-retaliation protections for employees, contractors, and unpaid advisors. Enforcement is through the Attorney General, with civil penalties up to $10 million per first violation and $30 million for subsequent violations of the safety requirements. Accredited colleges and universities engaged in academic research are excluded from the large developer definition.